GENOME-WIDE ASSOCIATION STUDY IMPLICATES NOVEL LOCI AND REVEALS CANDIDATE EFFECTOR GENES FOR LONGITUDINAL PEDIATRIC BONE ACCRUAL

Abstract Background Bone accrual impacts lifelong skeletal health, but genetic discovery has been primarily limited to cross-sectional study designs and hampered by uncertainty about target effector genes.Here, we capture this dynamic phenotype by modeling longitudinal bone accrual across 11,000 bone scans in a cohort of healthy children and adoles

Leptospermum petersonii (family Myrtaceae) is often cultivated for ornamental purposes but also serves as a rich source of bioactive essential oils.While several studies focused on the activities of the essential oils, this study analysed the potential of spent L.petersonii leaves as a natural food preservative.Method: We investigated the in vitro